You are here

Article Text

Article menu
Download PDFPDF
Research Article
Acetylcholine receptor turnover in mice with passively transferred myasthenia gravis. I. Receptor degradation.
  1. S Wilson,
  2. A Vincent,
  3. J Newsom-Davis
  1. Department of Neurological Science, Royal Free Hospital School of Medicine, London, UK.

    Abstract

    The in vivo degradation of endplate acetylcholine receptors was investigated in mice treated daily with IgG from 10 myasthenia gravis patients. Four preparations increased the rate of degradation. The number of endplate acetylcholine receptors after 7 days of IgG treatment was greater than that predicted on the basis of the increased degradation rate, suggesting a compensatory increase in receptor synthesis.

    https://doi.org/10.1136/jnnp.46.5.377

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.