Article Text


Manifesting heterozygosity in sex-linked spastic paraplegia?
  1. I D Young,
  2. I F Pye,
  3. J R Moore


    An unusual form of hereditary spastic paraplegia is described. Affected females have a late-onset slowly progressive spastic paraparesis. Affected males show oligophrenia with a rapidly progressive spastic quadriplegia. The mode of inheritance is consistent with sex-linkage, with partial manifestation in female carriers.

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