Article Text

PDF

Motor and cognitive performances of parkinsonian patients in the on and off phases of the disease.
  1. F Girotti,
  2. F Carella,
  3. M P Grassi,
  4. P Soliveri,
  5. R Marano,
  6. T Caraceni

    Abstract

    Twenty-one Parkinsonian patients were tested in on and off phases during chronic levodopa therapy for cognitive function, affective status, and evaluation of motor performance with reaction and movement times. A worsening of mood was observed from the on to the off phase. No variation in cognitive performance was observed from the on to the off phase in spite of evident motor changes. Mood changes during on-off variations may reflect involvement of mesocortical and mesolimbic dopaminergic systems.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.