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Proximal weakness of the extremities as main feature of amyloid myopathy.
  1. F G Jennekens,
  2. J H Wokke
  1. Department of Neurology, University Hospital, Utrecht, The Netherlands.

    Abstract

    Two patients with muscle weakness caused by amyloid myopathy are described. Characteristic features such as pseudohypertrophy and abnormal firmness, and tumours of muscles were absent. It is suggested that muscle weakness in amyloid myopathy is caused by layers of amyloid covering muscle fibres. In middle aged or elderly patients with proximal muscle weakness the diagnosis of amyloid myopathy should be considered.

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