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Electrophysiological observations in patients with motor neuron disease receiving a thyrotropin releasing hormone analogue (RX77368).
  1. R J Guiloff,
  2. E Stålberg,
  3. D J Eckland,
  4. S L Lightman
  1. Department of Neurology, Westminster Hospital, Charing Cross and Westminster Medical School, London, UK.

    Abstract

    Twenty nine patients with motor neuron disease receiving a thyrotropin releasing hormone analogue showed acute 25-30% increase in mean corrected fibre density and mean macro EMG median amplitude and area in brachial biceps muscle. The data are consistent with a direct or indirect action of the drug on anterior horn cells.

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