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Necrotising haemorrhagic encephalomyelopathy in an adult: Leigh's disease.
  1. G Delgado,
  2. J Gállego,
  3. T Tuñón,
  4. J J Zarranz,
  5. J A Villanueva

    Abstract

    A 21 year old male, well-nourished and non-alcoholic, died after five weeks illness. He had suffered epileptic fits, bilateral internuclear ophthalmoplegia, bulbar and pontine paralysis, tetraparesia, ataxia and dystonia. A CT brain scan showed low density lesions of the striatum bilaterally. Post-mortem studies revealed pathological anomalies compatible with Leigh's disease, although the presence of haemorrhages and involvement of the mamillary bodies could also suggest Wernicke's encephalopathy.

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