Article Text

PDF

Single photon emission tomography using 99mTc-HM-PAO in the investigation of dementia.
  1. D Neary,
  2. J S Snowden,
  3. R A Shields,
  4. A W Burjan,
  5. B Northen,
  6. N MacDermott,
  7. M C Prescott,
  8. H J Testa
  1. Department of Neurology, Manchester Royal Infirmary, UK.

    Abstract

    Single photon emission tomographic imaging of the brain using 99mTc HM-PAO was carried out in patients with a clinical diagnosis of Alzheimer's disease, non-Alzheimer frontal-lobe dementia, and progressive supranuclear palsy. Independent assessment of reductions in uptake revealed posterior hemisphere abnormalities in the majority of the Alzheimer group, and selective anterior hemisphere abnormalities in both other groups. The findings were consistent with observed patterns of mental impairment. The imaging technique has potential value in the differential diagnosis of primary cerebral atrophy.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.