J Neurol Neurosurg Psychiatry 51:1498-1502 doi:10.1136/jnnp.51.12.1498
  • Research Article

Dementia and cognitive impairment in Parkinson's disease.

  1. F Girotti,
  2. P Soliveri,
  3. F Carella,
  4. I Piccolo,
  5. P Caffarra,
  6. M Musicco,
  7. T Caraceni
  1. Istituto Neurologico C. Besta, Milan, Italy.


      The frequency of dementia, the clinical characteristics and the pattern of cognitive impairment were studied in 147 unselected Parkinsonian patients. Twenty-one patients (14.28%) were judged to be demented. They had a more severe and widespread cognitive deficit although they were affected particularly in those tests that already discriminated Parkinsonian patients from controls. A direct comparison of Parkinsonian dementia with other types of dementia is needed to validate the concept of subcortical dementia.