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Contingent negative variation in adults with Gilles de la Tourette syndrome.
  1. T C van Woerkom,
  2. C Fortgens,
  3. B J van de Wetering,
  4. C M Martens
  1. Department of Clinical Neurology, Municipal Hospitals, The Hague, The Netherlands.

    Abstract

    Three deflections or waves of the Contingent Negative Variation (CNV): the Slow Negative Wave (SNW), the Terminal CNV (TCNV) and the Post Imperative Negative Variation (PINV) were studied in 18 adults with Gilles de la Tourette syndrome and in 15 controls. The patients showed a reduced SNW, a normal TCNV and an increased PINV. Moreover, at the right parietal region the patients demonstrated a decreased SNW, TCNV and PINV. The results are discussed in relation to behavioral and neuropsychological disturbances found in Gilles de la Tourette syndrome.

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