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Short-term stability of single motor unit recordings in motor neuron disease: a macro EMG study.
  1. R J Guiloff,
  2. H Modarres-Sadeghi,
  3. E Stålberg,
  4. H Rogers
  1. Department of Neurology, Westminster Hospital, London, UK.

    Abstract

    Thirty five individual macro EMG motor unit potentials in 13 patients with motor neuron disease were recorded every 15 minutes during a 2 hour period. No significant change in amplitude or area was seen in 15 control units in nine patients or in 20 units in 11 patients receiving RX77368 0.2-0.3 mg/kg. The findings provide no evidence for an action of this long acting TRH analogue on the peripheral territory of motor units in motor neuron disease.

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