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PET and movement disorders.
  1. D J Brooks,
  2. R S Frackowiak
  1. MRC Cyclotron Unit, Hammersmith Hospital, London, UK.

    Abstract

    In this paper the use of PET for determining the patterns of disruption of both regional cerebral metabolism, and the pre- and post-synaptic dopaminergic systems, associated with movement disorders is reviewed. That the various akinetic-rigid syndromes result in distinctive PET findings is shown, making functional imaging valuable in their differential diagnosis. PET may also be useful for detecting the presence of sub-clinical disease in Huntington's disease and other inherited movement disorders.

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