Article Text

PDF

Paraneoplastic cerebellar degeneration and limbic encephalitis in a patient with adenocarcinoma of the colon.
  1. T Tsukamoto,
  2. R Mochizuki,
  3. H Mochizuki,
  4. M Noguchi,
  5. H Kayama,
  6. M Hiwatashi,
  7. T Yamamoto
  1. Department of Neurology, Fukushima Medical College, Japan.

    Abstract

    The rare association of two neurological paraneoplastic syndromes, paraneoplastic cerebellar degeneration and limbic encephalitis occurred in a 55 year old woman with a microscopic adenocarcinoma in a colonic polyp. Complete removal of the tumour by polypectomy brought about a favourable recovery from limbic encephalitis but the cerebellar ataxia remained. High titres of antineuronal nuclear antibody resembling anti-Hu were demonstrated in serum by immunohistochemistry using rat brain as a substrate. The antibody identified a protein band of 41 kDa on a Western immunoblot.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.