J Neurol Neurosurg Psychiatry 57:626-628 doi:10.1136/jnnp.57.5.626
  • Research Article

Daytime sleep in myotonic dystrophy is not caused by sleep apnoea.

  1. F G van der Meché,
  2. J M Bogaard,
  3. J C van der Sluys,
  4. R J Schimsheimer,
  5. C C Ververs,
  6. H F Busch
  1. Department of Neurology, University Hospital Rotterdam-Dijkzigt, The Netherlands.


      Daytime sleepiness is common in myotonic dystrophy and might be attributed to disturbed nocturnal breathing. Seventeen out of 22 patients complained of excessive daytime sleepiness, resembling "idiopathic hypersomnolence". Sleep apnoea might have contributed to daytime sleepiness in only three of 17 patients. Treatment with the central stimulant methylphenidate produced sustained benefit in seven out of 11 patients tested. Daytime sleepiness in myotonic dystrophy is usually caused by dysfunction of central sleep regulation and not by disturbed nocturnal breathing.

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