J Neurol Neurosurg Psychiatry 59:516-519 doi:10.1136/jnnp.59.5.516
  • Research Article

Spontaneous intracranial hypotension from a CSF leak in a patient with Marfan's syndrome.

  1. R J Davenport,
  2. S J Chataway,
  3. C P Warlow
  1. University of Edinburgh, Department of Clinical Neurosciences, Western General Hospital, Scotland.


      A patient with Marfan's syndrome had spontaneous intracranial hypotension secondary to a proved CSF leak. It is postulated that the leak was caused by minor, unrecognised trauma rupturing spinal arachnoid diverticula. The diverticula were probably pre-existing abnormalities complicating the Marfan's syndrome. It is concluded that patients with spinal meningeal defects may be at increased risk of developing CSF leaks, possibly secondary to unrecognised trauma.

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