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Working memory in medicated patients with Parkinson's disease: the central executive seems to work.
  1. N Fournet,
  2. O Moreaud,
  3. J L Roulin,
  4. B Naegele,
  5. J Pellat
  1. Service Neurologie et Neuropsychologie, Centre Hospitalier Universitaire de Grenoble, France.

    Abstract

    OBJECTIVE--To determine whether a deficit of the central executive can explain the attentional deficits of patients with Parkinson's disease. METHODS--Fifteen patients with idiopathic Parkinson's disease and 15 controls were given a dual task paradigm minimising motor demands and combining verbal, visual, or spatial span with two conditions of articulatory suppression. RESULTS--Although the spans were systematically lower in medicated parkinsonian patients than in controls, suggesting a decrease of central processing resources, there was no direct evidence for a deficit of the central executive. CONCLUSIONS--A deficit of the central executive either is not an inevitable feature of the disease, or is dependent on the nature of task (visuomotor v cognitive), or is corrected by dopaminergic medication.

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