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Expression of tenascin in astrocytic tumours: too much ado about nothing?
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The stroma of astrocytic tumours has been investigated in the past years by various authors. Among the proteins of the extracellular matrix tenascin is considered a very important molecule because of presumed links with the malignancy of the tumours and with the angiogenesis1 2 and also a possible target for therapy. To verify these opinions we have performed an immunohistochemical analysis of 10 astrocytic tumours of the cerebral hemispheres. The series of patients comprised six men and four women, ranging in age from 43 to 72 years; seven underwent …