The modern day neurologist attempting to maintain a semblance of current knowledge on multiple sclerosis has an awesome task ahead of him. A brief perusal of Medline will give him some idea of the size of the task ahead, as one of the most written about subjects in the neurological periodicals, articles number in their thousands every year and seem to be rising at an exponential rate. I offer my respects to anyone attempting to produce a comprehensive text book to provide a synopsis of current theories on the disease particularly since …