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J Neurol Neurosurg Psychiatry 64:636-642 doi:10.1136/jnnp.64.5.636
  • Paper

Intracranial aneurysms in three patients with disseminated Lyme borreliosis: cause or chance association?

Table 2

Laboratory results of borrelia tests and interval between onset of symptoms and antibiotic treatment of three patients with Lyme borreliosis associated with intracranial aneurysms

Patient No
1 2 3
Serum antibodies +
Proliferation of PBMC ND + ND
CSF antibodies (intrathecally produced) +
CSF PCR
Plasma PCR + (×2) + (×2)
Brain tissue PCR ND ND
Interval between onset of symptoms and treatment for Lyme borreliosis (months) >13 5 12
  • PBMC = peripheral blood mononuclear cells; PCR = polymerase chain reaction; + = positive; − = negative; ND = not done; (×2) = from two specimens obtained and analysed at different times.

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