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J Neurol Neurosurg Psychiatry 64:758-762 doi:10.1136/jnnp.64.6.758
  • Paper

Genetic polymorphisms adjacent to the CAG repeat influence clinical features at onset in Huntington’s disease

Table 3

Relation between patient genotype and nature of symptoms at onset

Onset features Patient genotype
CCG 7/7 CCG 7/X A/A A/B + B/B
% of patients % of patients
Neurological 41.2 34.5 46.7 29.7
Psychiatric/cognitive 27.4 24.1 22.2 27.0
Combined3-150 31.4 41.4 31.1 43.3
p Overall 0.70 0.45
  • 3-150 Association of two or three types of symptoms at onset (neurological / psychiatric / cognitive) within the first year of onset.

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