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J Neurol Neurosurg Psychiatry 65:177-183 doi:10.1136/jnnp.65.2.177
  • Paper

Routine follow up after head injury: a second randomised controlled trial

  1. D T Wade,
  2. N S King,
  3. F J Wenden,
  4. S Crawford,
  5. F E Caldwell
  1. Rivermead Rehabilitation Centre, Abingdon Road, Oxford OX1 4XD, UK
  1. Dr DT Wade, Rivermead Rehabilitation Centre, Abingdon Road, Oxford OX1 4XD, UK. Telephone 0044 1865 240321; fax 01865–200185.
  • Received 6 October 1997
  • Revised 12 January 1998
  • Accepted 30 January 1998

Abstract

OBJECTIVE To confirm that patients admitted to hospital with a head injury benefit from a routinely offered early intervention service.

PATIENTS AND METHODS A mixed rural and urban Health District of 560 000 people with two accident and emergency departments provided the setting. Existing routine services for most patients with head injury are minimal. All patients aged 16–65 years admitted to hospital after a head injury of any severity, with or without other injuries entered the trial. Prospective randomisation, with a block randomisation procedure was used to allocate all eligible patients to either: a group offered an additional service by a specialist team; or a group receiving existing standard services. Patients were assessed at follow up six months after injury. The primary outcome measure was the Rivermead head injury follow up questionnaire, a validated and reliable measure of social disability. The Rivermead post-concussion symptoms questionnaire was used to estimate severity of post-concussion symptoms. Each patient in the trial group was contacted 7–10 days after injury, and offered assessment and interventions as needed. These initially focused on the provision of information, support, and advice. Forty six per cent of patients in the trial group also received further outpatient intervention or additional support by telephone.

RESULTS 314 patients were registered: 184 were randomised into the trial group, 130 into the control group. For prognostic data, the groups were comparable at randomisation, and remained comparable when assessed at six months. 132 trial and 86 control patients were followed up at six months after injury. Patients’ post-traumatic amnesia ranged from mild (n=79, 40%), and moderate (n=62, 32%), to severe (n=38, 19%) and very severe (n=17, 9%). The trial group patients had significantly less social disability (p=0.01) and significantly less severe post-concussion symptoms (p=0.02) at follow up at six months after injury than the control group patients.

CONCLUSIONS The early interventions offered by a specialist service significantly reduced social morbidity and severity of post-concussion symptoms in trial group patients at six months after head injury. Recommendations about how specialist services should be targeted are made both in the light of these results and those from a previous randomised controlled trial.

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