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J Neurol Neurosurg Psychiatry 65:213-217 doi:10.1136/jnnp.65.2.213
  • Paper

Distribution of electrophysiological abnormality in Lambert-Eaton myasthenic syndrome

Table 2

Compound muscle action potential amplitudes measured before and one hour after 3,4-diaminopyridine

Muscle Pre 3,4-DAP Post 3,4-DAP
ADM 5.34 (4.43) 5.67 (5.21)
APB 6.02 (4.92) 8.47 (8.14)
Anconeus 0.99 (1.03) 1.32 (1.26)
Biceps 3.39 (4.04) 3.48 (4.76)
Trapezius 6.21 (3.45) 7.71 (4.29)2-150
  • Values are mean (SD) (n=9).

  • 2-150 p=0.008; significantly improved following 10 mg 3,4-diamimopyridine (Wilcoxon signed rank test).

  • ADM = abductor digiti minimi; APB = abductor pollicis brevis; 3,4-DAP = 3,4-diaminopyridine.

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