Comparison of QTc supine values to the individual number of body sites manifesting abnormal thermal perception in 20 patients with familial dysautonomia
| Patient No | Body sites with abnormal warm perception (n) | Body sites with abnormal cold perception (n) | Body sites with abnormal warm or cold perception (n) | QTc supine (ms) | Intolerance to tilt (+) or stair stepping (†) |
|---|---|---|---|---|---|
| 1 | 3 | 2 | 4 | 387 | |
| 2 | 3 | 2 | 4 | 398 | |
| 3 | 4 | 3 | 6 | 399 | |
| 4 | 3 | 4 | 4 | 401 | |
| 5 | 6 | 6 | 6 | 404 | |
| 6 | 4 | 2 | 4 | 406 | |
| 7 | 3 | 4 | 5 | 406 | +† |
| 8 | 2 | 1 | 2 | 410 | |
| 9 | 4 | 4 | 5 | 415 | |
| 10 | 2 | 4 | 5 | 415 | |
| 11 | 4 | 2 | 4 | 418 | +† |
| 12 | 3 | 4 | 4 | 420 | |
| 13 | 6 | 5 | 6 | 420 | |
| 14 | 5 | 4 | 6 | 422 | |
| 15 | 6 | 5 | 6 | 423 | |
| (16) | (6) | (6) | (6) | (423) | (+†) |
| 17 | 4 | 4 | 4 | 429 | + † |
| (18) | (6) | (6) | (6) | (429) | (†) |
| (19) | (6) | (6) | (6) | (455) | |
| 20 | 6 | 4 | 6 | 467 | +† |
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The number of body sites with abnormal warm or cold thresholds found in each patient correlates with the QTc supine values. QTc supine values v number of sites with abnormal cold perception: Rs = 0.57; p<0.01. QTc supine valuesv number of sites with abnormal warm perception: Rs = 0.59; p<0.001. QTc supine valuesv number of sites with abnormal warm or cold perception: Rs = 0.46; p<0.05. Numbers in parentheses refer to the three patients who had cardiac arrest within 12 months after study.
