Transient amnesia after perimesencephalic haemorrhage: the role of enlarged temporal horns
- Dr JW Hop, University Department of Neurology, PO Box 85500, 3508 GA Utrecht, The Netherlands. Telephone 0031 30 2507975; fax 0031 30 2522783; emailj.w.hop{at}neuro.azu.nl
- Received 16 January 1998
- Revised 31 March 1998
- Accepted 6 April 1998
Abstract
OBJECTIVES Although long term outcome of patients with perimesencephalic haemorrhage, a benign subset of subarachnoid haemorrhage, is excellent, some patients report an episode of amnesia for the first hours to days after the ictus. The relation between the occurrence of amnesia and the size of the ventricles on CT, including the temporal horns, were studied in patients with perimesencephalic haemorrhage.
METHODS Twenty seven consecutive patients with perimesencephalic haemorrhage were asked about the occurrence of amnesia. Age adjusted bicaudate indices and third ventricle sizes were calculated. Linear measurements of the temporal horn were taken in three directions: anterior-posterior, medial-lateral, and oblique. Additionally, enlargement of the temporal horns was assessed with the “naked eye”.
RESULTS Ten of the 27 patients reported an episode of transient amnesia; in these patients the mean sizes of the temporal horns were larger than in patients without amnesia, ranging from a factor of 1.7 for the medial-lateral measurement to a factor of 2.3 for the anterior-posterior measurement. Most of the patients with amnesia had relative bicaudate indices and relative third ventricle sizes> 1, and all had enlarged temporal horns at “naked eye” assessment.
CONCLUSION About one third of patients with perimesencephalic haemorrhage have an episode of amnesia shortly after the bleed. The occurrence of amnesia is associated with enlargement of the temporal horns, and might be explained by temporary hippocampal dysfunction.
