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J Neurol Neurosurg Psychiatry 65:778-780 doi:10.1136/jnnp.65.5.778
  • Short report

Desmopressin in the treatment of daytime urinary frequency in patients with multiple sclerosis

Urinary variables during placebo and desmopressin treatment

Run in Placebo Desmopressin p Value (placebo/ desmopressin)
Number of voids in 6 hours
(after treatment where applicable):
 Mean 3.2 3.1 2.4 0.0081-150
 SD 1.3 1.4 0.9
Mean urine volume in 6 hours
(after treatment where applicable):
 Mean 384 342 246 0.0061-150
 SD 166 166 99
Mean 24 hours urine volume (ml):
 Mean 1290 1272 1218 0.052
 SD 436 482 455
Number of night time voids:
 Mean 1.2 1.4 1.5 0.263
 SD 1.2 1.1 1.2
Serum sodium (mmol/l):
 Mean 139.9 139.7 139.2
 SD 3.0 3.0 3.3
  • 1-150 Significant difference (p<0.05).

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