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J Neurol Neurosurg Psychiatry 65:822-827 doi:10.1136/jnnp.65.6.822
  • Paper

Subacute combined degeneration: clinical, electrophysiological, and magnetic resonance imaging findings

Table 2

Somatosensory evoked potentials in SCD

Patient Neuropathy Before and after substitution with Vitamin B12
Median nerve SEPs Tibial nerve SEPs
N9 (ms) N13 (ms) N20 (ms) N22 (ms) P37 (ms)
A Right Demyelinating 11.1 (10.5) 20.4 (16.5) 26.1 (21.6) NR (NR) 49.2 (46.2)
Left Demyelinating 11.1 (10.2) 19.5 (16.8) 27.3 (22.2) NR (NR) 53.4 (55.2)
B Right No  9.6 (ND) 15.9 (ND) 21 (ND) NR (NR) 46 (52.8)
Left No 10.8 (ND) 15.9 (ND) 20.7 (ND) NR (NR) 54 (53.4)
C Right No 11.6 (10.5) NR (15.3) 24.8 (21) NR (NR) 48.8 (51)
Left No 12.8 (10.5) NR (NR) 24 (21) NR (25.8) 65 (58.2)
D Right Mild axonal 10.8 (ND) 14.6 (ND) 21 (ND) 22 (NR) 54 (51)
Left Mild axonal 10.6 (ND) NR (ND) 21.4 (ND) 22 (NR) 50 (48.6)
E Right Mild axonal NR (NR) 15.9 (NR) 21.6 (21) NR (NR) 55 (47.4)
Left Mild axonal NR (NR) 15.3 (16.5) 21.6 (22.2) NR (NR) 49.8 (49.2)
F Right No  9.7 (8.4) NR (12) 21.6 (18.9) NR (18.6) 61.6 (40.8)
Left No  9.8 (8.4) NR (12.3) 20.8 (18.9) NR (18.6) 58.8 (40.2)
G Right No NR (ND) 14.7 (ND) 22.2 (ND) NR (NR) 48 (47.3)
Left No 10.5 (ND) 14.7 (ND) 22.2 (ND) NR (NR) 48 (49.6)
H2-150 Right Axonal 12.3 16.2 23.4 28.2 55.2
Left Axonal 11.7 17.1 23.5 28.2 56.4
I2-150 Right Axonal ND 18.4 23.6 NR 55.2
Left Axonal ND 17.6 23.2 NR 49.8
  • 2-150 Patients H and I died of unrelated diseases before follow up examination could be performed

  • Numbers in parenthises represent latencies after treatment. NR=no response; ND=not done.

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