This book is a brave attempt to discuss the burgeoning field of gene therapy for neurological disorders. To many clinicians, gene therapy has not to date lived up to all the hype and excitement of when it was first suggested. However, as the editors point out in their preface, this has been a little unfair and it remains an exciting area that is worthy not only of intellectual interest but also the possibilities of therapy in the future. The complexities, however, of this technique, cannot be overestimated. Neurons are postmitotic; a brain has a degree …