rss
J Neurol Neurosurg Psychiatry 1999;66:702 doi:10.1136/jnnp.66.6.702
  • Editorial commentary

Case-control study of presenelin-1 intronic polymorphism

  1. JULIE WILLIAMS,
  2. PATRICK G KEHOE,
  3. MICHAEL J OWEN
  1. Division of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, Wales, UK
  1. Dr Julie Williams, Division of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, Wales, UK.

    There is no doubt that candidate gene association studies can play a useful part in detecting genetic variations contributing to complex diseases such as Alzheimer’s disease.1 Yasudaet al present a paper in this issue (pp772-6) in which they use this approach to test for an association between the 1-1 genotype of an intronic polymorphism in the presenilin 1 (PS-1) gene and Alzheimer’s disease, originally reported by Wragget al.2 Although Yasudaet al did not replicate this effect …

    [Full text of this article]

    This Article

    1. Extract
    2. Full text
    3. PDF

    Responses

    1. Submit a response
    2. No responses published

    Register for free content

    The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

    Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

    BMJ Careers - Latest neurology and neurosurgery jobs