Creutzfeldt-Jakob-like syndrome induced by lithium, levomepromazine, and phenobarbitone
- Shemaron 201, 3–12–28 Negishi, Taito-ku
- Tokyo 110, Japan
- 1–5–45 Yushima Bunkyo-ku, Tokyo 113, Japan
- Dr Hideyuki Kikyo, Department of Neurology, Tokyo Medical and Dental University, Tokyo, Japan. email:kikyo{at}m.u-tokyo.ac.jp
- Shemaron 201, 3–12–28 Negishi, Taito-ku
- Tokyo 110, Japan
- 1–5–45 Yushima Bunkyo-ku, Tokyo 113, Japan
- Dr Hideyuki Kikyo, Department of Neurology, Tokyo Medical and Dental University, Tokyo, Japan. email:kikyo{at}m.u-tokyo.ac.jp
Creutzfeldt-Jakob-like syndrome was first reported by Smith and Kocen1 in 1988. Its symptoms resemble Creutzfeldt-Jakob disease but it is induced by drugs, particularly lithium, and most patients recover without sequel after discontinuation of drugs. It also displays a characteristic EEG similar to Creutzfeldt-Jakob disease, but this returns to normal when the patient recovers.
There have been some case reports of Creutzfeldt-Jakob-like syndrome after that of Smith et al (table), but no paper seems to have described the detailed course of EEG changes. This paper presents a case of Creutzfeldt-Jakob-like syndrome possibly induced by lithium, levomepromazine, and phenobarbitone, in which we succeeded in recording the course of EEG changes.
- In this window
- In a new window
Creutzfeldt-Jakob-like syndrome related to lithium
A 65 year old woman was admitted to a hospital with coma and myoclonus. She had a history of manic and …
