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Intracranial extracerebral follicular lymphoma mimicking a sphenoid wing meningioma
  1. DOMINIC J HODGSON,
  2. KAROLY M DAVID,
  3. MICHAEL POWELL
  1. Department of Surgical Neurology
  2. Department of Neuropathology, The National Hospital for Neurology and Neurosurgery
  3. Department of Pathology, University College Hospital, London, UK
  1. Mr Michael Powell, Department of Surgical Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, United Kingdom. Telephone 0044 171 837 3611; fax 0044 171 209 3875.
  1. JAN L HOLTON
  1. Department of Surgical Neurology
  2. Department of Neuropathology, The National Hospital for Neurology and Neurosurgery
  3. Department of Pathology, University College Hospital, London, UK
  1. Mr Michael Powell, Department of Surgical Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, United Kingdom. Telephone 0044 171 837 3611; fax 0044 171 209 3875.
  1. FRANCESCO PEZZELLA
  1. Department of Surgical Neurology
  2. Department of Neuropathology, The National Hospital for Neurology and Neurosurgery
  3. Department of Pathology, University College Hospital, London, UK
  1. Mr Michael Powell, Department of Surgical Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, United Kingdom. Telephone 0044 171 837 3611; fax 0044 171 209 3875.

https://doi.org/10.1136/jnnp.67.2.251

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    Primary lymphoma in the brain is uncommon, accounting for only 2% of primary intracranial neoplasms,1 although its incidence seems to be dramatically increasing.2Leptomeningeal lymphomas are even rarer but have been described1 3 4; however, no leptomeningeal lymphoma of the follicular type has previously been reported. We present a case of a primary meningeal follicular lymphoma which mimicked a sphenoid wing meningioma, both radiologically and intraoperatively.

    A 57 year old Ghanaian woman was referred with a 3 year history of worsening bitemporal headache, followed by a 6 month history of daily right frontal headache lasting for 2–3 hours associated with mild photophobia. There were no reports of seizures, nausea, or other visual disturbances. Her medical history was 3 years of treated hypertension, sickle cell carrier trait, and a cataract extraction. The patient was obese but physical examination was otherwise normal. Neurological examination showed no papilloedema and there were no cranial nerve or long tract signs.

    Brain CT showed an …

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