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J Neurol Neurosurg Psychiatry 67:395-397 doi:10.1136/jnnp.67.3.395
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Primary torsion dystonia: the search for genes is not over

Table 3

Two point LOD scores for selected chromosome 8 and 18 markers spanning the DYT6 and DYT7 loci

LOD score
at θ=
0 0.05 0.1 0.2 0.3
Family 1:
 Chromosome 8 D8S1791 −3.15 −1.43 −0.88 −0.39 −0.15
D8S260 −2.8 −0.23 −0.01 0.1 0.08
D8S286 −2.8 −0.19 0.02 0.12 0.09
 Chromosome 18 D18S59 −3 −1.29 −0.76 −0.3 −0.11
D18S452 −6.19 −1.44 −0.89 −0.39 −0.15
D18S843 −2.7 −0.72 −0.44 −0.19 −0.08
Family 2:
 Chromosome 8 D8S1791 −2.2 0.07 0.23 0.24 0.13
D8S1113 −2.2 −1.15 −0.67 −0.25 −0.09
D8S279 −2.5 −1.15 −0.63 −0.2 −0.04
 Chromosome 18 D18S59 −2.75 −0.97 −0.63 −0.29 −0.12
D18S54 −2.5 −1.17 −0.67 −0.25 −0.09
D18S391 −3.1 −0.72 −0.44 −0.19 −0.08
Family 3:
 Chromosome 8 D8S1791 −5.48 −1.81 −1.3 −0.79 −0.45
D8S260 −5.48 −1.28 −0.73 −0.27 −0.09
D8S286 −2.53 −0.63 −0.43 −0.29 −0.21
 Chromosome 18 D18S59 −5.48 −1.81 −1.3 −0.79 −0.45
D18S52 −2.85 −1.53 −0.99 −0.49 −0.24
D18S452 −5.61 −1.4 −0.93 −0.55 −0.34
Family 4:
 Chromosome 8 D8S1791 −5.84 −2.99 −2.07 −0.98 −0.42
D8S260 −4.68 −1.89 −1.23 −0.6 −0.31
D8S286 −5.5 −0.91 −0.43 −0.07 0.05
 Chromosome 18 D18S59 −4.33 −1.94 −1.29 −0.51 −0.16
D18S52 −4.05 −1.73 −1.16 −0.48 −0.17
D18S452 −7.69 −2.63 −1.82 −0.78 −0.25
Family 5:
 Chromosome 8 D8S1791 −3.14 −1.54 −0.99 −0.47 −0.22
D8S260 −5.47 −1.11 −0.62 −0.25 −0.1
D8S1119 −5.96 −1.57 −1.01 −0.48 −0.22
 Chromosome 18 D18S59 −5.45 −1.62 −0.87 −0.28 −0.08
D18S1154 −5.13 −0.58 −0.16 0.08 0.05
D18S967 −5.45 −1.48 −0.98 −0.53 −0.3

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