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J Neurol Neurosurg Psychiatry 68:238-241 doi:10.1136/jnnp.68.2.238
  • Short report

Late onset levodopa responsive Huntington's disease with minimal chorea masquerading as Parkinson plus syndrome

Patient characteristics

Age Disease duration (y) Initial diagnosis Estimated IQ CAG Repeat length Levodopa Family history Chorea Dystonia SEMG
Dose mg/day Response
63 5 MSA 91 18/43 400 ++ P ± AB
67 7 PD/MSA 95 19/44 800 +++ P CC/LL ND
52 7 ARS 94 17/46 200 + C/HD UL ND
68 4 MSA NA 17/42 400 ++ P/E/M ± LL ND
  • P=parkinsonism; C=chorea; E=epilepsy; M=motor neuron disease; ARS=akinetic-rigid syndrome; NA=not available; ND=not done; CC=craniocervical; LL=lower limb; UL=upper limb; AB=abnormal.

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