Table 2
The Talairach atlas35 location of brain regions' peak, Bonferroni corrected, significance for the statistical map shown in the figure.
| Structure (Brodmann area) | Talairach coordinates (x, y, z) | Peak z score (p Value) |
| Left medial orbital frontal (BA 11) | −11, 46, −14 | 6.2 (<0.0001) |
| Left anterior cingulate (BA 32) | −9, 14, 46 | 8.5 (<0.0001) |
| Left dorsolateral frontal (BA 4) | −58, −5, 29 | 6.5 (<0.0001) |
| Left dorsolateral frontal (BA 8) | −39, 23, 37 | 5.4 (<0.0001) |
| Left dorsolateral parietal (BA 40) | −57, −52, 28 | 5.2 (<0.0001) |
| Left pulvinar | −12, −26, 9 | 4.5 (<0.0001) |
| Left ventral striatum | −16, 13, 8 | 5.2 (<0.0001) |
| Left cerebellum | −11, −59, −13 | 7.4 (<0.0001) |
| Right dorsolateral frontal (BA 4) | 53, −7, 49 | 6.6 (<0.0001) |
| Right dorsolateral frontal (BA 6) | 59, −2, 28 | 9.3 (<0.0001) |
| Right medial frontal (BA 8) | 11, 27, 42 | 4.7 (<0.0001) |
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These locations were derived from normalised brain perfusion, as measured by 99mTc-HMPAO SPECT. The map reflects regions with significantly lower perfusion in 10 patients with Alzheimer's disease who had significantly more delusions and hallucinations compared with 10 patients with Alzheimer's disease who were matched demographically and across all other behaviours measured by the NPI.
