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Högyes studied medicine at the University of Budapest and received his degree in 1870. From 1875 to 1883 he was Professor of Pathology and Therapeutics at the University of Kolosvar and was at various times Rector of the Faculty and Rector of the Medical Department at Budapest University. After Pasteur's success in developing a vaccination for rabies, the Research Institute of Rabies was established at Budapest by Högyes. Antirabies serum was manufactured at the Institute and he contributed to the treatment of this dreaded disease. Högyes was awarded the Hungarian Medical Academy prize for this contribution. He was internationally known and in 1954 was postally honoured with other scientists by Hungary as a great physician and scientist (Stanley Gibbons 1397, Scott 1108).