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Unilateral caudate head lesion simulating brain tumour in X-linked adult onset adrenoleukodystrophy
  1. R SAKAKIBARA,
  2. T FUKUTAKE,
  3. K ARAI,
  4. K KATAYAMA,
  5. M MORI,
  6. T HATTORI
  1. Neurology Department Chiba University, 1–8–1 Inohana Chuo-Ku, Chiba 260–8670 Japan
  2. Neurology Department Kashima Rosai Hospital
  3. 1–9108–2 Doai-Honmachi Hasaki
  4. Kashima 314–03 Japan
  1. Dr R Sakakibara sakaki{at}med.m.chiba-u.ac.jp
  1. R SAKAKIBARA,
  2. T FUKUTAKEK,
  3. K KATAYAMA,
  4. M MORI
  1. Neurology Department Chiba University, 1–8–1 Inohana Chuo-Ku, Chiba 260–8670 Japan
  2. Neurology Department Kashima Rosai Hospital
  3. 1–9108–2 Doai-Honmachi Hasaki
  4. Kashima 314–03 Japan
  1. Dr R Sakakibara sakaki{at}med.m.chiba-u.ac.jp

https://doi.org/10.1136/jnnp.70.3.414

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    The appearance of X-linked adrenomyeloneuropathy (AMN)/adrenoleukodystrophy (ALD) on MRI is usually specific, with bilateral symmetric areas of white matter abnormality surrounding the posterior horns of the lateral ventricles with various degrees of atrophy of the spinal cord.1 Our patient with AMN, however, showed a lesion in the right caudate head simulating a brain tumour, which has not been a feature in this disease.

    At the age of 25 the patient started to have progressive spastic paraparesis and mild ataxia with genitourinary dysfunction (urge urinary incontinence and erectile dysfunction).2 On admission to our hospital at the age of 34, T2 weighted MR images showed …

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