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This new multiauthor text attempts the ambitious task of reviewing in inclusive detail the wide range of pituitary function, dysfunction, clinical assessment, and management of pituitary tumours. The editors, three of whom are pathologists, are eminent in this field and they have assembled an outstanding list of contributors. A sound scientific background is provided in specific chapters, which are devoted to anatomy, physiology, pathophysiology, pathology, and molecular pathogenesis, and remains evident in the subsequent chapters dealing with medical, surgical, and radiotherapeutic approaches to management of specific tumour types. All chapters provide authoritative and valuable reviews and conclusions drawn are based on a thorough assessment of the literature. There are, of course, some overlaps between individual chapters with a common theme—for example, molecular pathogenesis—but this is not disadvantageous and allows each contribution to stand alone. This notwithstanding, the editors have achieved overall cohesion of presentation so that the book can be viewed as a whole and not simply a collection of reviews. It is inevitable that the time required to complete such a large project means that some important recent developments, such as the discovery of the natural ligand for the growth hormone releasing peptide receptor, could not have been included in the excellent chapter on hypothalamic-pituitary physiology and regulation. Any criticism of this book would be minor but I was disappointed that an otherwise very thorough chapter on neuro-ophthalmological evaluation did not deal with the more practical aspects of clinical assessment including choice of methods for field assessment. Overall, the editors have achieved their stated aim of providing information in a single book which is of value to the various specialists who treat patients with pituitary mass lesions and function as members of a multidisciplinary team. I would strongly recommend it to clinical endocrinologists, to neurosurgeons seeking an in depth knowledge of the endocrinological aspects of pituitary mass lesions, and to neuroendocrine pathologists who will appreciate the breadth of coverage and the extent to which discussion of pathogenesis, pathology, and clinical management have been skilfully combined.
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