Data on experimental and control subjects in study
| No of subjects | Sex | Scan age (days) | R vol (mm3) | L vol (mm3) |
Hippo vol ratio |
R T2 (ms) |
L T2 (ms) |
ECC-scan (days) |
ECC Dur (min) |
FH | Fever | Focal | Recur | Preg/birth |
| Patients with ECC: | ||||||||||||||
| 1 | F | 871 | 2364 | 2378 | 1.01 | 105 | 107 | 9 | 30 | Y | Y | HT | N | N / Blue |
| 2 | M | 396 | 2039 | 2367 | 1.16 | 115 | 116 | 8 | 45 | N | Y | L | N | N / Pro |
| 3 | M | 1662 | 2880 | 2635 | 1.09 | 109 | 105 | 5 | 30 | Y | N | G | N | N / N |
| 4 | F | 311 | 1935 | 1935 | 1.00 | 124 | 120 | 13 | 35 | Y | Y | G | N | N / Pro |
| 5 | M | 384 | 2903 | 2160 | 1.34 | 123 | 119 | 9 | 150 | Y | Y | G | N | N / Pro |
| 6 | M | 269 | 2074 | 2157 | 1.04 | 127 | 125 | 13 | 5 | N | Y | R | N | N / Csn |
| 7 | F | 508 | 2817 | 3525 | 1.25 | 121 | 111 | 13 | 40 | N | Y | G | N | N / Csn |
| 8 | F | 503 | 2722 | 2239 | 1.22 | 107 | 112 | 10 | 20 | N | Y | L | N | Bld / N |
| 9 | M | 520 | 2091 | 1970 | 1.06 | 124 | 124 | 7 | 135 | Y | Y | G | Y | Bld / Csn |
| 10 | M | 354 | 2474 | 2848 | 1.15 | 126 | 121 | 11 | 2 | N | Y | G | Y | N / N |
| 11 | M | 531 | 2748 | 2661 | 1.03 | 123 | 121 | 14 | 180 | Y | N | G | N | N / Ind |
| 12 | M | 518 | 2903 | 2129 | 1.36 | 114 | 114 | 14 | 40 | Y | Y | R | Y | Ind / N |
| 13 | F | 670 | 2575 | 2367 | 1.09 | 141 | 129 | 14 | 30 | Y | Y | R | Y | N / Csn |
| 14 | M | 723 | 2402 | 2350 | 1.02 | 112 | 103 | 5 | 20 | N | N | R | N | N / N |
| 15 | M | 386 | 2170 | 1922 | 1.13 | 125 | 121 | 14 | 30 | N | Y | G | N | N /N |
| 16 | F | 764 | 1827 | 1866 | 1.02 | 123 | 115 | 13 | 30 | N | N | G | N | N / N |
| 17 | M | 409 | 2091 | 2160 | 1.03 | 135 | 130 | 12 | 45 | Y | N | G | N | N / N |
| 18 | M | 811 | 1866 | 1617 | 1.15 | 135 | 122 | 4 | 90 | N | Y | G | N | N / N |
| Mean | 525 | 2353 | 2274 | 1.12 | 122 | 118 | 11 | 53 | ||||||
| (SD) | (182) | (372) | (438) | (0.11) | (9) | (7) | (3) | (51) | ||||||
| Sex |
Scan age (days) |
R vol (mm3) |
L vol (mm3) |
Hippo vol ratio |
Reason for MRI | |||||||||
| Control subjects: | ||||||||||||||
| 19 | F | 970 | 2986 | 3069 | 1.03 | Occulomotor nerve angioma/neurofibroma | ||||||||
| 20 | M | 461 | 1440 | 1373 | 1.05 | Cleft palate | ||||||||
| 21 | M | 1560 | 1360 | 1350 | 1.01 | Dysarthria, spastic dysplegia | ||||||||
| 22 | M | 607 | 3093 | 2989 | 1.03 | Hypotonia, poor visual development | ||||||||
| 23 | M | 549 | 1852 | 1839 | 1.01 | Hypotonia, visual impairment, cortical myoclonus | ||||||||
| 24 | M | 1383 | 3380 | 3338 | 1.01 | Idiopathic growth hormone deficiency | ||||||||
| 25 | F | 332 | 1167 | 1145 | 1.02 | Pituitary mass | ||||||||
| 26 | F | 1380 | 1720 | 1802 | 1.04 | Craniopharyngioma | ||||||||
| 27 | F | 366 | 2876 | 2944 | 1.02 | Abnormality of pituitary stalk/hypothalamus | ||||||||
| 28 | M | 564 | 2227 | 2400 | 1.07 | Dysmorphic features with developmental delay | ||||||||
| Mean | 817 | 2210 | 2225 | 1.03 | ||||||||||
| (SD) | (442) | (772) | (779) | (0.02) | ||||||||||
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Subjects with hippocampal ratios⩾1.09 are shown inbold typeface; ECC scan=time in days between convulsion and MRI scan; ECC dur=duration of convulsion; FH=family history of epilepsy; Fever=presence of fever on arrival at hospital; Focal =any focal features (R, L = right or left hemiconvulsion) or whether generalised (G); Recur=recurrence of seizures in 24 hour period; HT=head turning; N=normal; Csn=caesarian section; Pro=prolonged labour; Bld=vaginal bleeding during pregnancy; Ind=induced labour; Patient 3 (in italics) was excluded because of clinical and EEG evidence of benign childhood epilepsy, and the data were not included in means and SD calculations for the “patients with ECC” group).
