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J Neurol Neurosurg Psychiatry 72:26-30 doi:10.1136/jnnp.72.1.26
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Heart rate dynamics in refractory and well controlled temporal lobe epilepsy

Table 4

Heart rate and measures of heart rate variability in patients with TLE and control subjects

Measure/ variable Patients with refractory TLE (n=9) Patients with well controlled TLE (n=25) All patients (n=44) Control subjects (n=4) p Value‡ (Mann-Whitney)
RRI (ms) 863 (103) 819 (112) 838 (109) 850 (71) 0.403
SDNN (ms) 154 (32) 158 (51) 156 (43) 177 (44) 0.039
VLF (ms2) 1538 (762) 1749 (1005) 1658 (905) 3256 (1765) <0.001
LF ( ms2) 905 (472) 1038 (507) 981 (491) 1901 (1308) 0.001
HF (ms2) 604 (502) 628 (365) 618 (424) 1710 (2050) 0.011
ApEn 0.93 (0.21)† 1.09 (0.32) 1.02 (0.29) 1.15 (0.21) 0.045
α1 1.22 (0.18) 1.17 (0.18) 1.19 (0.18 1.16 (0.1) 0.292
α2 1.03 (9.0) 0.99 (7.64)* 1.01 (8.45) 1.01 (6.13) 0.824
Slope of HRV −1.32 (0.13) −1.37 (0.21) −1.35 (0.18) −1.20 (0.21) 0.002
Values are mean (SD); RRI, R-R interval; SDNN, SD of all RRIs; VLF, very low frequency; LF, low frequency; HF, high frequency; ApEn, approximate entropy; α1, short term scaling exponent; α2, long-term scaling exponent; *p=0.037 compared with the patients with refractory TLE; †p=0.021 compared to the patients with well controlled TLE; ‡ all patients compared with the control subjects.

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