Table 4
The relation between tertiles of cerebral haemodynamic variables and depression expressed as odds ratios
| Odds ratios* (95% CI) | ||||
|---|---|---|---|---|
| Tertile | Number of subjects | CES-D score ≥16 (n=116) | Subthreshold depressive disorder† (n=59) | Depression‡ (n=40) |
| Note: the numbers of cases with subthreshold depressive disorder and depressive disorder do not add up to 116 because five subjects had no psychiatric work-up and 12 screen positive subjects had other psychiatric diseases or a previous stroke. | ||||
| *Logistic regression adjusted for age, sex, and cognitive function. | ||||
| †Subjects with depression or a history of stroke excluded from analysis. | ||||
| ‡Subjects with subthreshold depressive disorder or a history of stroke excluded from analysis. | ||||
| Mean blood flow velocity (range in cm/s) | ||||
| 1st (54.4 to 112) | 692 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 2nd (44.8 to 54.3) | 697 | 1.2 (0.7 to 2.0) | 1.1 (0.6 to 2.1) | 1.2 (0.5 to 2.9) |
| 3rd (14.8 to 44.7) | 703 | 1.9 (1.2 to 3.1) | 1.5 (0.8 to 2.7) | 2.6 (1.2 to 5.8) |
| End diastolic blood flow velocity (range in cm/s) | ||||
| 1st (35.6 to 83.5) | 694 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 2nd (28.1 to 35.5) | 692 | 1.0 (0.6 to 1.7) | 0.8 (0.4 to 1.6) | 1.2 (0.5 to 2.8) |
| 3rd (8.0 to 28.0) | 705 | 1.8 (1.1 to 2.9) | 1.2 (0.7 to 2.3) | 2.5 (1.1 to 5.5) |
| Peak systolic blood flow velocity (range in cm/s) | ||||
| 1st (93.6 to 170) | 695 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 2nd (77.0 to 93.5) | 692 | 1.3 (0.8 to 2.1) | 1.2 (0.6 to 2.2) | 1.2 (0.5 to 2.7) |
| 3rd (37.0 to 77.0) | 706 | 1.7 (1.0 to 2.7) | 1.5 (0.8 to 2.7) | 2.0 (0.9 to 4.3) |
| Vasomotor reactivity (range in %/kPa) | ||||
| 1st (4.48 to 22.9) | 669 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 2nd (2.67 to 4.47) | 674 | 2.2 (1.3 to 3.8) | 2.8 (1.3 to 6.4) | 1.6 (0.7 to 3.5) |
| 3rd (0.05 to 2.66) | 671 | 2.0 (1.2 to 3.5) | 3.0 (1.3 to 6.7) | 1.2 (0.5 to 2.7) |
