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J Neurol Neurosurg Psychiatry 73:701-704 doi:10.1136/jnnp.73.6.701
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Multiple Sclerosis Impact Scale (MSIS-29): reliability and validity in hospital based samples

Table 3

Convergent and discriminant construct validity of the MSIS-29

MSIS-29
Rehabilitation sample Corticosteroid sample PPMS sample Community sample
Instrument Scale/dimension/ variable MSIS-29 Physical MSIS-29 Psychological MSIS-29 Physical MSIS-29 Psychological MSIS-29 Physical MSIS-29 Psychological MSIS-29 Physical MSIS-29 Psychological
*Medical Outcomes Study 36-item Short Form Health Survey: high scores = better health. †Functional Assessment of Multiple Sclerosis: high scores = better health. ‡General Health Questionnaire.
SF-36* Physical functioning −0.52 −0.28 −0.70 −0.44 −0.73 −0.30 −0.79 −0.41
Mental health −0.39 −0.73 −0.46 −0.77 −0.30 −0.64 −0.41 −0.76
FAMS† Mobility −0.63 −0.27 −0.75 −0.61 −0.75 −0.45 −0.88 −0.50
Emotional wellbeing −0.51 −0.67 −0.50 −0.74 −0.56 −0.75 −0.68 −0.68
GHQ‡ Total score 0.51 0.77 0.52 0.78 0.36 0.68 0.46 0.68
EDSS 0.27 0.14 0.69 0.48
Demographic variables Age −0.01 −0.06 −0.03 −0.16 −0.16 −0.09 0.22 0.03
Sex −0.01 −0.02 −0.20 −0.16 0.19 0.06 0.05 −0.05
Years since diagnosis 0.09 0.09 0.18 −0.17 0.19 −0.02 0.19 0.03

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