Peripheral nerve granuloma in a patient with tuberculosis
- 1University Department of Clinical Neurosciences, Royal Free and University College Medical School, University College London, London, UK
- 2Department of Neurology, Royal Free Hospital, London, UK
- 3North Middlesex Hospital, London, UK
- Correspondence to: Dr R W Orrell, Department of Clinical Neurosciences, Royal Free and University College Medical School, University College London, Rowland Hill Street, London NW3 2PF, UK; r.orrell{at}rfc.ucl.ac.uk
- Received 31 May 2002
- Accepted 30 August 2002
- Revised 21 August 2002
Abstract
The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include an immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, a meningitic reaction, and the toxic effects of antituberculous chemotherapy. This report describes the unusual finding of granulomas in the peripheral nerve of a patient with tuberculosis. The pathological findings were of a delayed hypersensitivity reaction, but with no more specific indications of the mechanism of the neuropathy.
Footnotes
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Competing interests: none declared.
