Summary of current drug treatments for nystagmus*
| *For details see refs 2 and 3. | |
| Vestibular forms of nystagmus | |
| Peripheral imbalance | Diphenhydramine, promethazine, prochlorperazine, ondansetron for relief of attendant vertigo and nausea; resume activities as soon as able |
| Central imbalance | |
|
Clonazepam, baclofen, trihexyphenidyl; acetazolamide (for nystagmus associated with episodic ataxia type II) |
|
Baclofen |
| Central instability | |
|
Baclofen |
| Nystagmus associated with visual system disorder | |
|
Baclofen, clonazepam, alcohol, gabapentin |
| Nystagmus from disorders of the gaze holding mechanism | |
|
In association with disease of central myelin: gabapentin, memantine, clonazepam, trihexyphenidyl, scopolamine; cannabis, alcohol |
| As part of the syndrome of oculopalatal tremor (“myoclonus”): gabapentin, valproate trihexyphenidyl | |
| Saccadic intrusions and oscillations | |
|
Methylphenidate |
|
Clonazepam, popranolol, gabapentin, corticosteroids, intravenous immunoglobulin, plasma exchange |
| Miscellaneous abnormal movements | |
|
Gabapentin, carbamazepine, popranolol |
|
Carbamazepine |
