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J Neurol Neurosurg Psychiatry 2003;74:1606-1607 doi:10.1136/jnnp.74.12.1606
  • Mesial temporal atrophy
  • Editorial commentary

Why study mesial temporal atrophy in patients with intractable temporal lobe epilepsy?

  1. F Andermann
  1. McGill University, 3801 University Street, Room 127, Montreal, Canada H3A 2B4
  1. Correspondence to: Professor F Andermann; frederick.andermannmcgill.ca

    The paper by Bonilha et al in this issue (pp 1627–1630) represents yet another step in clarifying the significance of atrophy of mesial temporal structures beyond the hippocampus.1

    One of the major advances in the imaging of patients with temporal lobe epilepsy was recognition of hippocampal atrophy, now visible and quantifiable, based on high quality magnetic resonance imaging.2 Measurements of the amygdala volume, carried out in addition to volumetric studies of the hippocampus, provided insights into the significance of the clinical symptom presentation in patients who turned out to have prominent amygdaloid atrophy. Much less clear is the significance of …

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