Article Text
Abstract
Objectives: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging.
Methods: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls.
Results: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated.
Conclusions: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
- idiopathic intracranial hypertension
- magnetic resonance imaging
- diffusion
- proton longitudinal relaxation time
- ADC, apparent diffusion coefficient
- DW-MRI, diffusion weighted magnetic resonance imaging
- EP, echo planar
- IIH, idiopathic intracranial hypertension
- IR, inversion recovery
- ROI, region of interest
- TI, inversion time
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Footnotes
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Competing interests: none declared