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J Neurol Neurosurg Psychiatry 2003;74:147-148 doi:10.1136/jnnp.74.2.147-a
  • Dementia
  • Editorial commentary

Dipoles and dementia

  1. C M Epstein
  1. Emory Clinic, Department of Neurology, 1365 Clifton Road, Atlanta, GA 30322, USA
  1. Correspondence to:
 Dr C M Epstein;
 chipstein{at}aol.com

    Can the link between MEG dipoles and cortical activity lead to increased applications for the unique capabilities of MEG?

    For almost two decades magnetoencephalography (MEG) has been the stepchild of functional neuroimaging. Despite its evolution from single sensors to arrays of more than 100, with unmatched temporal resolution, the legitimacy of MEG as a clinical and research tool has been repeatedly challenged. On the one hand, neurophysiologists persistently—and appropriately—question the advantage of MEG over scalp-recorded electroencephalograms and evoked potentials when the latter are analysed by sophisticated algorithms. On the other hand, advocates of functional magnetic resonance imaging (MRI) and positron emission tomography have disparaged MEG because of the assumptions …

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