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J Neurol Neurosurg Psychiatry 74:423-426 doi:10.1136/jnnp.74.4.423
  • Paper

Onset age and severity of motor impairment are associated with reduction of myocardial 123I-MIBG uptake in Parkinson’s disease

Table 1

Ratio of 123I-metaiodobenzylguanidine uptake in the heart to that in the mediastinum in four subgroups of patients with Parkinson’s disease and in healthy control subjects

Early image Delayed image
Patient subgroup Median Range Median Range
*p < 0.005;
**p < 0.0001 compared with controls.
Older/severe 1.30* ** 1.10–1.76 1.17* ** 0.90–1.76
Older/mild 1.40** 1.12–2.60 1.27** 1.03–1.93
Younger/severe 1.50** 1.16–2.22 1.31** 1.17–2.49
Younger/mild 1.63* ** 1.27–2.45 1.42* ** 1.09–2.34
Controls 2.26 1.92–2.77 2.19 1.93–2.55

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