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J Neurol Neurosurg Psychiatry 74:743-748 doi:10.1136/jnnp.74.6.743
  • Paper

Should asymptomatic patients with hereditary haemorrhagic telangiectasia (HHT) be screened for cerebral vascular malformations? Data from 22 061 years of HHT patient life

Table 5

Relative risk of any cerebral events under the age of 45 years as illustrated by the standardised ratio

Event type Number of strokes Incidence ratio (95% CI) Standardised ratio (95% CI)
CI, confidence interval.
Definite haemorrhage
All 22 1.25 (0.79 to 1.90) 13.89 (8.70 to 21.03)
Male 16 1.84 (1.05 to 2.99) 22.99 (13.14 to 37.33)
Female 6 0.68 (0.25 to 1.48) 6.18 (2.27 to 13.45)
Definite and probable haemorrhage
All 26 1.48 (0.97 to 2.17) 16.5 (10.7 to 24.1)
Male 18 2.07 (1.23 to 3.27) 25.7 (15.2 to 40.6)
Female 8 0.91 (0.39 to 1.79) 8.24 (3.56 to 16.25)
Abscess
All 15 0.89 (0.48 to 1.41) 9.87 (5.52 to 16.28)
Male 8 0.92 (0.40 to 1.81) 11.4 (4.9 to 22.5)
Female 7 0.79 (0.32 to 1.63) 7.22 (2.90 to 14.87)
Other strokes
All 11 0.63 (0.31 to 1.12) 7.00 (3.50 to 12.54)
Male 4 0.46 (0.13 to 1.18) 5.71 (1.56 to 14.63)
Female 7 0.79 (0.32 to 1.63) 7.22 (2.90 to 14.87)
All strokes
All 52 2.96 (2.21 to 3.89) 32.9 (24.6 to 43.2)
Male 30 3.45 (2.32 to 4.93) 42.9 (28.9 to 61.2)
Female 22 2.49 (1.56 to 3.78) 22.7 (14.2 to 34.3)

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