Entacapone is beneficial in both fluctuating and non-fluctuating patients with Parkinson’s disease: a randomised, placebo controlled, double blind, six month study

D J Brooks; H Sagar; The Uk-Irish Entacapone Study Group

doi:10.1136/jnnp.74.8.1071

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Paper

Entacapone is beneficial in both fluctuating and non-fluctuating patients with Parkinson’s disease: a randomised, placebo controlled, double blind, six month study

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	Abstract	Full	Pdf
Jul 2003	123	195	154
Aug 2003	64	482	209
Sep 2003	36	146	80
Oct 2003	24	122	50
Nov 2003	18	53	43
Dec 2003	9	56	24
Jan 2004	11	49	8
Feb 2004	13	41	34
Mar 2004	7	51	25
Apr 2004	6	26	24
May 2004	2	36	34
Jun 2004	18	35	28
Jul 2004	51	74	16
Aug 2004	48	61	70
Sep 2004	38	48	38
Oct 2004	36	65	40
Nov 2004	24	76	48
Dec 2004	34	45	32
Jan 2005	23	79	30
Feb 2005	14	69	34
Mar 2005	23	82	72
Apr 2005	6	85	55
May 2005	17	50	48
Jun 2005	14	49	40
Jul 2005	19	51	48
Aug 2005	17	44	50
Sep 2005	8	61	56
Oct 2005	14	57	43
Nov 2005	11	53	57
Dec 2005	13	42	27
Jan 2006	18	43	24
Feb 2006	7	57	44
Mar 2006	20	59	40
Apr 2006	13	41	38
May 2006	19	34	17
Jun 2006	9	49	29
Jul 2006	15	46	30
Aug 2006	12	25	14
Sep 2006	6	34	17
Oct 2006	18	20	29
Nov 2006	6	39	18
Dec 2006	14	46	28
Jan 2007	22	29	20
Feb 2007	13	23	29
Mar 2007	11	27	30
Apr 2007	21	13	10
May 2007	10	8	8
Jun 2007	10	9	11
Jul 2007	11	13	16
Aug 2007	11	9	7
Sep 2007	4	10	15
Oct 2007	11	13	10
Nov 2007	7	8	11
Dec 2007	9	9	8
Jan 2008	9	8	7
Feb 2008	18	9	15
Mar 2008	18	11	16
Apr 2008	23	9	19
May 2008	14	7	7
Jun 2008	11	11	15
Jul 2008	11	6	10
Aug 2008	8	5	4
Sep 2008	20	12	9
Oct 2008	16	12	12
Nov 2008	22	10	7
Dec 2008	4	11	5
Jan 2009	11	3	8
Feb 2009	21	4	9
Mar 2009	20	17	14
Apr 2009	15	4	11
May 2009	11	2	4
Jun 2009	10	5	3
Jul 2009	8	7	4
Aug 2009	8	2	7
Sep 2009	4	6	5
Oct 2009	9	4	9
Nov 2009	18	7	12
Dec 2009	6	2	4
Jan 2010	32	1	3
Feb 2010	14	1	3
Mar 2010	9	3	9
Apr 2010	14	3	3
May 2010	17	2	4
Jun 2010	4	3	5
Jul 2010	12	0	2
Aug 2010	4	1	3
Sep 2010	5	6	6
Oct 2010	22	2	6
Nov 2010	25	7	9
Dec 2010	7	6	3
Jan 2011	23	11	11
Feb 2011	13	5	4
Mar 2011	16	4	7
Apr 2011	20	3	7
May 2011	9	4	6
Jun 2011	10	3	3
Jul 2011	8	8	5
Aug 2011	6	5	4
Sep 2011	5	7	4
Oct 2011	12	3	3
Nov 2011	19	6	5
Dec 2011	16	13	14
Jan 2012	6	23	10
Feb 2012	11	15	6
Mar 2012	5	13	8
Apr 2012	16	12	12
May 2012	22	18	4
Jun 2012	23	12	11
Jul 2012	25	22	8
Aug 2012	16	16	9
Sep 2012	24	20	17
Oct 2012	22	15	18
Nov 2012	30	30	17
Dec 2012	12	27	11
Jan 2013	28	13	6
Feb 2013	24	24	25
Mar 2013	21	19	25
Apr 2013	29	27	12
May 2013	9	13	8
Jun 2013	12	14	3
Jul 2013	9	9	5
Aug 2013	7	18	13
Sep 2013	7	8	9
Oct 2013	8	11	5
Nov 2013	22	7	10
Dec 2013	16	12	6
Jan 2014	9	21	11
Feb 2014	15	18	14
Mar 2014	25	21	16
Apr 2014	16	29	11
May 2014	19	18	13
Jun 2014	16	19	14
Jul 2014	23	33	22
Aug 2014	29	27	19
Sep 2014	27	41	21
Oct 2014	23	45	5
Nov 2014	12	38	7
Dec 2014	13	19	4
Jan 2015	12	81	4
Feb 2015	5	16	9
Mar 2015	17	16	10
Apr 2015	12	8	2
May 2015	11	11	6
Jun 2015	17	3	10
Jul 2015	9	7	5
Aug 2015	18	10	7
Sep 2015	20	4	5
Oct 2015	19	7	7
Nov 2015	21	10	9
Dec 2015	20	15	9
Jan 2016	25	6	6
Feb 2016	11	10	5
Mar 2016	18	3	2
Apr 2016	13	11	9
May 2016	13	9	6
Jun 2016	11	4	6
Jul 2016	16	5	3
Aug 2016	19	7	2
Sep 2016	32	8	6
Oct 2016	21	31	7
Nov 2016	17	46	9
Dec 2016	18	21	5
Jan 2017	37	7	12
Feb 2017	5	3	7
Mar 2017	17	34	20
Apr 2017	10	32	3
May 2017	2	22	5
Jun 2017	6	16	5
Jul 2017	23	15	1
Aug 2017	23	19	3
Sep 2017	30	20	6
Oct 2017	20	14	2
Nov 2017	41	31	4
Dec 2017	30	22	6
Jan 2018	42	26	8
Feb 2018	29	17	5
Mar 2018	51	25	11
Apr 2018	40	36	5
May 2018	47	27	3
Jun 2018	33	21	4
Jul 2018	29	15	5
Aug 2018	35	23	11
Sep 2018	52	38	18
Oct 2018	42	28	14
Nov 2018	64	54	13
Dec 2018	43	41	6
Jan 2019	56	54	7
Feb 2019	53	49	7
Mar 2019	28	24	10
Apr 2019	31	17	18
May 2019	32	18	13
Jun 2019	19	17	5
Jul 2019	33	27	17
Aug 2019	38	30	11
Sep 2019	44	38	5
Oct 2019	34	32	11
Nov 2019	43	31	7
Dec 2019	68	64	15
Jan 2020	34	32	16
Feb 2020	36	32	8
Mar 2020	45	43	26
Apr 2020	28	28	12
May 2020	41	39	10
Jun 2020	25	23	4
Jul 2020	48	47	20
Aug 2020	33	25	13
Sep 2020	46	46	8
Oct 2020	69	61	30
Nov 2020	55	47	15
Dec 2020	53	41	5
Jan 2021	61	53	12
Feb 2021	52	46	15
Mar 2021	42	38	11
Apr 2021	43	37	17
May 2021	40	40	9
Jun 2021	45	45	12
Jul 2021	65	67	15
Aug 2021	70	69	30
Sep 2021	42	41	8
Oct 2021	50	36	32
Nov 2021	37	29	21
Dec 2021	46	47	11
Jan 2022	37	31	11
Feb 2022	39	37	7
Mar 2022	44	46	9
Apr 2022	26	25	11
May 2022	63	58	14
Jun 2022	45	43	16
Jul 2022	50	42	10
Aug 2022	51	39	7
Sep 2022	42	32	14
Oct 2022	136	75	8
Nov 2022	69	57	10
Dec 2022	53	43	15
Jan 2023	68	54	19
Feb 2023	58	56	4
Mar 2023	66	51	20
Apr 2023	51	45	25
May 2023	21	15	7
Jun 2023	36	26	7
Jul 2023	50	52	16
Aug 2023	37	30	19
Sep 2023	43	28	12
Oct 2023	68	68	7
Nov 2023	100	86	9
Dec 2023	172	19	1
Jan 2024	66	6	0
Feb 2024	51	3	0
Mar 2024	86	4	1
Total	6665	7474	3871

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