Article Text
Abstract
Objective: To investigate the state of spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis.
Methods: Fifteen subjects suffering a first neurological episode suggestive of multiple sclerosis in clinical presentation, immunological profile, and magnetic resonance imaging, were examined with a new, sensitive test of spatial vision, rarebit perimetry. None had symptoms or signs of optic neuropathy.
Results: Results of rarebit perimetry were significantly worse than those of 15 age matched normal controls (p=0.01); seven patients (47%) were outside normal limits. One patient only obtained abnormal results in high pass resolution perimetry.
Conclusions: Rarebit perimetry may help to close the sensitivity gap between clinical examinations and neuroimaging.
- demyelination
- multiple sclerosis
- spatial vision
- perimetry
- MS, multiple sclerosis
- MRI, magnetic resonance imaging
- HRP, high pass resolution perimetry