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Spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis
  1. L Frisén
  1. Institute of Clinical Neuroscience, Sahlgren’s Academy of Göteborg University, Sweden
  1. Correspondence to:
 Dr L Frisén, Neuro-ophthalmology, Sahlgren’s Hospital, SE-413 45 Göteborg, Sweden; 
 lars.frisen{at}neuro.gu.se

Abstract

Objective: To investigate the state of spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis.

Methods: Fifteen subjects suffering a first neurological episode suggestive of multiple sclerosis in clinical presentation, immunological profile, and magnetic resonance imaging, were examined with a new, sensitive test of spatial vision, rarebit perimetry. None had symptoms or signs of optic neuropathy.

Results: Results of rarebit perimetry were significantly worse than those of 15 age matched normal controls (p=0.01); seven patients (47%) were outside normal limits. One patient only obtained abnormal results in high pass resolution perimetry.

Conclusions: Rarebit perimetry may help to close the sensitivity gap between clinical examinations and neuroimaging.

  • demyelination
  • multiple sclerosis
  • spatial vision
  • perimetry
  • MS, multiple sclerosis
  • MRI, magnetic resonance imaging
  • HRP, high pass resolution perimetry

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