Table 1
Clinical characteristics of the affected individuals
| ID | Sex (age) | Age at onset of paralytic attacks | Frequency of paralytic attacks | HyperK+ during attacks | Duration of episodes | Precipitant factors | Cardiac arrhythmia | Response to drugs | Site of paramyotonia |
|---|---|---|---|---|---|---|---|---|---|
| RAE, rest after exercise; CTH, cold temperature and humidity; ACZ, acetazolamide; CT, chlorothiazide; SLB, salbutamol. | |||||||||
| II:2 | F (81) | <1 y | 1/day | no | 1–15 min | fasting, CTH | no | – | – |
| II:3 | F (79) | <1 y | 1–3/day | – | 20 min | RAE, CTH, stress | – | – | – |
| II:4 | F (76) | <1 y | 1–3/day | – | 10 min | fasting, CTH | yes | – | – |
| II:6 | M (73) | <1 y | 1/day | no | 20 min | RAE, fasting, carrots | yes | no (ACZ, CT) | hand |
| III:1 | M (46) | 6–7 months | 1–2/day | no | 10 min–2 h | RAE, fasting, CTH, alcohol | no | no (ACZ) | eyes, hand |
| III:3 | M (45) | 8 months | 1–2/day | no | 1 h | – | no | no (ACZ, SLB) | eyes |
| III:5 | M (38) | 9 months | 2–3/day | no | 15 min | RAE, CTH | no | no (ACZ) | – |
| IV:1 | M (18) | 6 months | 1–2/week | yes | 20 min | RAE, fasting, CTH | – | – | eyes, hand |
| IV:2 | M (16) | 8 months | 1–2/week | – | 20 min | RAE, CTH | – | – | |
